The Life Raft Group is pleased to announce the release of the eighth issue of The GIST Cancer Journal, the official journal of the Life Raft Group and the first academic journal devoted solely to GIST. The journal is intended to serve as a comprehensive and authoritative resource of scientifically valid information for physicians and allied health care professionals regarding advances in the diagnosis and treatment of GIST. Editorial content focuses on the impact of translational research in oncology and gastroenterology relating specifically to GIST. As the official medical journal of the Life Raft Group, it also provides a forum for GIST patient advocacy. It is published quarterly.

In this issue of the GIST Cancer Journal

The GIST Cancer JournalArticles in this month’s journal highlight a case study of a patient with PDGFRA D842V mutation, an interview with insights into the potential of immunotherapy in GIST treatment, and a review of posters from CTOS 2015.

Dr. Jonathan Trent, editor of the GIST Cancer Journal, discusses in his editor’s memo the correlation between GIST and soft tissue sarcomas, and the exciting possibilities of collaborating in research efforts.

A case study, entitled : A Patient with a High-Risk Resected Gastric GIST Tumor and a PDGFRA D842V Mutation  authored by Christie Hancock, MD, Rachel Mitchell, MD, Lei Yan, MD and William Leslie, MD, all of Rush University Medical Center, outlines the challenges in treatment for a specific patient with this GIST mutation.

A summary from the 2015 CTOS (Connective Tissue Oncology) Meeting describes posters related to GIST. CTOS Sessions Redefine Combination Therapies, Sequential Management Strategies in GIST and Related Sarcomas.

Finally, the world of immunotherapy for GIST is explored in an interview with Andrew E. Rosenberg, MD, Vice Chair of the Department of Pathology, Director of Bone and Soft Tissue Service and Professor of Pathology at the University of Miami, Miami Florida. Exploring the Enormous Potential of Immunotherapy in GIST and Its Microenvironment.

Please visit the Journal’s website to learn more and to read articles from the current issue. Print copies and article reprints can also be ordered via the website by contacting either

View the GIST Cancer Journal Archives