Is it time to cure GIST?
Dr. Brian Rubin I’ve been working on a cure for GIST most of my professional life and the initial work was both exciting and fulfilling. I remember when we confirmed the presence [...]
LRG researchers publish ‘cell sleep’ study
Members of the Life Raft Group Research Team continue to publish results of promising studies aimed at finding a cure for GIST. The latest reflects the collaboration that guides its efforts.
LRG researchers publish study on DREAM complex – an important regulator of GIST “cell sleep”
A study about the DREAM complex was published in the June issue of Cancer Research by LRG Research Team members Drs. Anette Duensing and Maria Debiec-Rychter.
How ‘Next Generation’ DNA sequencing is changing the landscape of GIST research and diagnosis
During the past dozen years gastrointestinal stromal tumors have emerged from oncologic obscurity and reached center-stage in the development of targeted therapies for solid tumors. Tyrosine kinase inhibitors (TKIs) like imatinib, sunitinib, and more recently regorafenib, have proven effective in suppressing the growth of metastatic GIST, allowing patients to live far longer than during the previous era of ineffective chemotherapy.
Breaking Research Barriers – Our Unique Team Searches for a Cure
Breaking Research Barriers! The Life Raft Group Research Team is unique. As we know, the purpose of research is to inform, educate and allow us to live better lives.
A Cure is Within Our Grasp
A Cure is Within Our Grasp! It is amazing what happens when you change what doesn't work - Our Life Raft Group Research Team is a great example of this
ETV1 inhibitor takes lead in combination approach to clinical trials
MSKCC is launching a clinical trial that uses a MEK inhibitor to target ETV1 in combination with imatinib on a small group of newly diagnosed GIST patients
LRG Research Team identifies critical role of CDC37 in GIST tumors
Adrian Mariño-Enriquez explains the significance of a recently published study that will have a big impact on GIST research. Keep reading to learn the critical role of CDC37 in GIST tumors.
DOG1 Gene and GIST – What is the Relationship?
Jonathan Fletcher and Sebastian Bauer of the LRG’s Research Team were among the authors in a study to be published in Cancer Research that examined the relationship between GIST and the expression of the gene DOG1.
It Will Take Not One Hero but Many: Collaborating for a Cure
Time magazine this month published an in-depth look at how collaboration is beginning to change the way cancer research is approached, citing numerous examples of the effectiveness of scientists working together to find a cure.