Liz Skree at the NIH Pediatric & Wild-type GIST Clinic
Liz Skree at the NIH Pediatric & Wild-type GIST Clinic
Leah Knopp at the NIH Pediatric & Wild-type GIST Clinic
Leah Knopp at the NIH Pediatric & Wild-type GIST Clinic
Josalin Dunn at the NIH Pediatric and Wild-type GIST Clinic
Josalin Dunn at the NIH Pediatric & Wild-type GIST Clinic
Pat George: the man, the myth, the legend
Pat George, LRG member and volunteer is well-known in the community. Pat recently took it upon himself to help educate the local students
KIT signaling & new approaches for GIST therapy
KIT functions in several distinct cell types. Keep reading to learn about KIT signaling and new approaches for GIST Therapy.
Hereditary GIST explained
This article explains hereditary GIST. Familial cancer syndrome is a genetic condition that causes an increased risk for specific types of cancers. Familial cancer syndromes account for only five to ten percent of all [...]
FDA Approves Gleevec to Prevent Recurrence of Rare Gastrointestinal Cancer
Gleevec was approved by the Food and Drug Administration (FDA) to prevent Gastrointestinal Cancer(imatinib mesylate) for a new indication. This will keeping cancer from growing in patients following surgical removal of a gastrointestinal stromal tumor [...]
Defining molecular mechanisms of imatinib treatment in GIST
Gastrointestinal stromal tumors (GISTs) are caused by mutations in the KIT or PDGFRA (platelet-derive growth factor receptor alpha) receptor tyrosine kinase genes and can successfully be treated with imatinib mesylate
Fifth LRG Poker Tournament a Success
On November 20, 2008, the LRG held its Fifth Annual Poker Tournament at the Midtown Loft on Fifth Avenue in New York City. It is always a remarkable evening and has become a muchlooked- forward-to event for LRG staff and supporters.
Questions to Consider for Adjuvant Treatment
GIST patients face many decisions about their treatment. Many GIST patients have surgery to remove a primary tumor and do not have detectable metastases at the time of surgery. This large group of patients faces the decision of whether or not to take Gleevec to try to prevent or delay a recurrence. Adjuvant therapy refers to additional treatment given after a main mode of therapy (the main treatment is usually surgery). For example, Gleevec given after surgery in hopes of preventing or delaying a recurrence is called adjuvant therapy.