Radiation therapy revisited as an option in GIST treatment
Radiation therapy has been revisited as an option in GIST treatment. Keep reading to learn more about the research that has gone into radiation therapy.
How ‘Next Generation’ DNA sequencing is changing the landscape of GIST research and diagnosis
During the past dozen years gastrointestinal stromal tumors have emerged from oncologic obscurity and reached center-stage in the development of targeted therapies for solid tumors. Tyrosine kinase inhibitors (TKIs) like imatinib, sunitinib, and more recently regorafenib, have proven effective in suppressing the growth of metastatic GIST, allowing patients to live far longer than during the previous era of ineffective chemotherapy.
New Blood Testing Technology May Be Effective in Detecting Mutations
A new blood testing technology may lead to major changes in treatment of Gastrointestinal Stromal Tumors. In a study presented in April by Dr. George Demetri of the Dana-Farber Cancer Institute at the American Association for Cancer Research annual meeting, the blood test was shown to be more effective than traditional biopsies in identifying secondary mutations in GIST.
Carrie Broussard and Her ‘Little Brave Warrior’
Carrie Broussard gave birth to a healthy baby boy on May 1, after finding out she was pregnant in the midst of treatment with Gleevec. She named him Caelum, which in the Celtic origin means ‘brave warrior’ and in the Australian origin means ‘a gift.”
Marathon Brings GIST Awareness to Richmond, VA
The numbers of marathon walkers, runners and spectators who gathered in support of Dana Pearson’s GIST fundraiser in Virginia was both heartwarming and astonishing.
ETV1 inhibitor takes lead in combination approach to clinical trials
MSKCC is launching a clinical trial that uses a MEK inhibitor to target ETV1 in combination with imatinib on a small group of newly diagnosed GIST patients
Clinical Trials and the Search for Greater Efficiency
Clinical trials are a key step in the development and approval of new drugs to treat cancer and often a lifeline to patients seeking options when other treatments have failed.
GIST Patient Meets the Challenge of Motherhood
While there are many physical challenges that come with raising a child when you are living with GIST, Dana Pearson puts her energy into conquering the mental ones.
LRG Research Team identifies critical role of CDC37 in GIST tumors
Adrian Mariño-Enriquez explains the significance of a recently published study that will have a big impact on GIST research. Keep reading to learn the critical role of CDC37 in GIST tumors.
Personalized Medicine – Another Look
The issue of personalized medicine, also referred to as "precision medicine" in the article, was addressed in a newsletter article by LRG Executive Director Norman Scherzer in February. We hope to follow up with more articles on the topic soon.