The Life Raft Group has received two recent reports of patients that had failed multiple therapies and then apparently responded to Nexavar (also known as sorafenib or BAY 43-9006). In both cases, the patients had failed Gleevec, Sutent and AMN107. Anecdotal reports like this should be viewed with considerable caution. Carefully designed clinical trials are […]
The Latest News from the Life Raft Group
Building blocks of tumor progression
This is the eighth article in a series written by each of the key members of the LRG Resistance Research Team. Several articles in the LRG newsletter from our GIST Resistance Research Team have been written over the last year, focusing mainly on the role of KIT and PDGFRA mutation in the genesis and treatment […]
Carney-Stratakis Syndrome
Sept, 2007 – A diverse group of researchers has found the genetic defects that cause a rare type of familial GIST called “Carney-Stratakis syndrome”. This syndrome has some similarities to Carney’s Triad but it is a distinct entity. This discovery may one day lead to better treatments for the affected patients and may give researchers […]