Dr. Alexander Drilon of Memorial Sloan Kettering Cancer Center recently reported at AACR on a potential new cancer treatment, Entrectinib, a receptor tyrosine kinase (RTK) inhibitor developed to target tumors carrying NTRK1, NTRK2, NTRK3, [...]
If you have a mutation of any of the SDH subunits (a,b,c, or d), the next important question to ask is whether or not it is a germline mutation. (So far, data has indicated that 80% of SDH-deficient tumors are germline). The term "germline" means that the mutation is present in every cell of your body. Germline mutations are hereditary, and can be passed on to your children. For this reason, genetic testing and counseling could be informative for parents, siblings and other family members. If a family member tests positive for the mutation, this does not mean that they will get GIST.
"I'm glad I called the Life Raft Group. They rallied around me and told me I'm going to make it and get through this GIST journey of mine and conquer this cancer." - [...]
The second annual Water of Life whisky fundraiser was a night to remember! This year’s event, hosted by Dr. Matt Lurin to benefit the Life Raft Group, was held at Midtown Loft & Terrace [...]
A few weeks ago, Chris Carley lost his battle with GIST and the Life Raft Group lost one of its heroes. He was 73 and had been fighting his battle with GIST since 1995. He [...]
On June 29th, LRG Executive Director, Norman Scherzer, will be attending Vice President Joe Biden’s “National Moonshot Summit,” at Howard University. A “by invitation only” event, the summit is designed to bring together scientists, [...]
We are in the midst of one of the most exciting times in history to be involved in cancer research. Over 60 anti-cancer drugs have gained FDA-approval in the last 10 years, and that [...]
On March 19, 2014, the Centers for Medicare & Medicaid Services (CMS) issued federal guidance on third-party insurance payments for the new Exchange plans offered under the Affordable Care Act (ACA). In direct contradiction [...]
Members of Team-J's Charity Bicycling Team are planning to bicycle in Ride Across America in support of two causes; Hydrocephalus Awareness - www.hydroassoc.org GIST Pediatric Cancer Awareness - www.liferaftgroup.org Donate Now TEAM-J's local [...]
A recent announcement from the University of Texas MD Anderson Cancer Center described a study that shows promise for a potential treatment (LOXO-101) that targets solid tumors with NTRK gene fusions. The investigational agent, [...]
