ASCO features many updates on GIST trials. Promising results for the immunotherapy approach to treating cancer dominated the annual conference of the ASCO and represent one of the biggest developments in cancer research since the advent [...]
Jonathan Fletcher and Sebastian Bauer of the LRG’s Research Team were among the authors in a study to be published in Cancer Research that examined the relationship between GIST and the expression of the gene DOG1.
The LRG research team meets four times a year, with at least one in-person meeting per year. This year, the team held its in-person meeting at the LRG office in New Jersey March 22-24, 2013.
Join our Tissue Bank - Help the LRG in the search for a cure. Wildtype GIST tissue is needed for a current LRG Research Team project. If you or a loved one are a wildtype GIST patient, please help the LRG Research Team in its search for the cure by donating your tissue.
First report of a GIST patient responding to a BRAF inhibitor. Dr. Gerald Falchook and colleagues at MD Anderson Cancer Center provided the first report of a GIST patient responding to a BRAF inhibitor. The BRAF gene is frequently mutated in melanoma and BRAF inhibitors provide one of the most important therapies available for melanoma patients
Treatment guidelines for GIST are established by experts to ensure that patients receive adequate care and appropriate therapies.
Since we have gotten a number of questions about Gleevec (imatinib) plasma levels and testing, I think it’s time to revisit the subject, especially for newer members. Since this is a very complex subject, this may take a few emails and a few days.
Patients with GIST who received sunitinib using a flexible dose approach to manage adverse events remained on treatment longer than those who received the strict dose/schedule and exhibited better clinical outcomes (longer time to tumor progression and longer overall survival).
When your blood doesn't have enough healthy red blood cells or have enough hemoglobin, you can tire quickly or feel weak. This condition is called anemia. The fatigue that comes with anemia can lead to a decreased quality of life. Some fatigue is not related to anemia. Anemia has three broad causes; blood loss, decreased blood cell production and increased blood cell destruction. The first two are the most relevant for GIST patients.
Stivarga comes in 40 mg tablets. Once opened, it must be used within 28 days. Stivarga must be stored in the bottle that it comes in, the desiccant must remain in the bottle; keep bottle tightly sealed. Do not store in a daily or weekly pill box.